????????????? ??? ?????? ????????? ???? ?? ????? ?????? ??????? ??????????? ??????????? ??? ???? ??? ????? ?????? ??????????? ????????? ?? ??????? ??? ???? ??? ????? ????? ??????? ???????.Advise both individuals and caregivers with regards to the risks of respiratory melancholy and sedation when OPANA ER is utilized with benzodiazepines or other CN